This web page was produced as an assignment for Genetics 677, an undergraduate course at UW-Madison.
Future Directions
Since women who experience POF are encouraged to undergo estrogen replacement therapy, there can be many side implications. Not only does the FoxO3 gene work as a tumor suppressor and has been shown to initiate cancer as well as POF, but the estrogen therapy also plays a role in cancer development, especially breast cancer.
1) What is Akt
2) PI3K/AKT/mTOR pathway
3) Synthetic activator of PI3K pathway
Since women who experience POF are encouraged to undergo estrogen replacement therapy, there can be many side implications. Not only does the FoxO3 gene work as a tumor suppressor and has been shown to initiate cancer as well as POF, but the estrogen therapy also plays a role in cancer development, especially breast cancer.
1) What is Akt
2) PI3K/AKT/mTOR pathway
3) Synthetic activator of PI3K pathway
